RESUMEN
In this research, some plant seeds powder was evaluated to find their potential effect to rule diseases of food poisoning. Antimicrobial effect of five plant seeds was examined contra Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella. pneumonia and Candida albicans by using well diffusion method. Antimicrobial activity studies revealed high potential activity of plant seeds powder of Nigella sativa L., cucurbita pepo, Sesamum radiatum, Trigonella foenum-graecum, Linum usitatissimum with variable efficiency contra tested microbial strains with concentration of 100 mg/ml, except Sesamum radiatum scored no effect. The T. foenum and N. sativa seed powder showed the largest inhibition zone (24-20 mm) contra K. pneumonia, followed by S. aureus (20-18 mm) and C. albicans (15mm) respectively. The five plant seeds powder exhibited bacteriostatic and bactericidal effects with MIC's 20 and MBC 40 mg/ml against K. pneumonia, and MIC's 40 and MBC 60 mg/ml against S. aureus. The results of this study indicated that plants seeds powder have promising antimicrobial activities and their potential applications in food process. It could be utilized as a natural medicinal alternative instead of chemical substance.
Nesta pesquisa, o pó de sementes de plantas foi avaliado para encontrar seu efeito potencial no controle de doenças de intoxicação alimentar. O efeito antimicrobiano de cinco sementes de plantas foi examinado contra Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia e Candida albicans usando o método de difusão bem. Estudos de atividade antimicrobiana revelaram alto potencial de atividade de sementes de plantas em pó de Nigella sativa L., Cucurbita pepo, Sesamum radiatum, Trigonella foenum-graecum, Linum usitatissimum com eficiência variável contra cepas microbianas testadas com concentração de 100 mg / ml, exceto Sesamum radiatum com pontuação não efeito. O pó de sementes de T. foenum e N. sativa apresentou a maior zona de inibição (24-20 mm) contra K. pneumonia, seguido por S. aureus (20-18 mm) e C. albicans (15 mm), respectivamente. O pó de cinco sementes de plantas exibiu efeitos bacteriostáticos e bactericidas com MIC's 20 e MBC 40 mg / ml contra K. pneumonia, enquanto MIC's 40 e MBC 60 mg / ml contra S. aureus. Os resultados deste estudo indicaram que os pós de sementes de plantas apresentam promissoras atividades antimicrobianas e suas potenciais aplicações em processos alimentícios. Ele poderia ser utilizado como alternativa medicinal natural em vez de substância química.
Asunto(s)
Staphylococcus aureus , Enfermedades Transmitidas por los Alimentos , Semillas , Extractos Vegetales/farmacología , Pruebas de Sensibilidad Microbiana , Antibacterianos/farmacologíaRESUMEN
In this research, some plant seeds powder was evaluated to find their potential effect to rule diseases of food poisoning. Antimicrobial effect of five plant seeds was examined contra Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella. pneumonia and Candida albicans by using well diffusion method. Antimicrobial activity studies revealed high potential activity of plant seeds powder of Nigella sativa L., cucurbita pepo, Sesamum radiatum, Trigonella foenum-graecum, Linum usitatissimum with variable efficiency contra tested microbial strains with concentration of 100 mg/ml, except Sesamum radiatum scored no effect. The T. foenum and N. sativa seed powder showed the largest inhibition zone (24-20 mm) contra K. pneumonia, followed by S. aureus (20-18 mm) and C. albicans (15mm) respectively. The five plant seeds powder exhibited bacteriostatic and bactericidal effects with MIC's 20 and MBC 40 mg/ml against K. pneumonia, and MIC's 40 and MBC 60 mg/ml against S. aureus. The results of this study indicated that plants seeds powder have promising antimicrobial activities and their potential applications in food process. It could be utilized as a natural medicinal alternative instead of chemical substance.
Nesta pesquisa, o pó de sementes de plantas foi avaliado para encontrar seu efeito potencial no controle de doenças de intoxicação alimentar. O efeito antimicrobiano de cinco sementes de plantas foi examinado contra Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia e Candida albicans usando o método de difusão bem. Estudos de atividade antimicrobiana revelaram alto potencial de atividade de sementes de plantas em pó de Nigella sativa L., Cucurbita pepo, Sesamum radiatum, Trigonella foenum-graecum, Linum usitatissimum com eficiência variável contra cepas microbianas testadas com concentração de 100 mg / ml, exceto Sesamum radiatum com pontuação não efeito. O pó de sementes de T. foenum e N. sativa apresentou a maior zona de inibição (24-20 mm) contra K. pneumonia, seguido por S. aureus (20-18 mm) e C. albicans (15 mm), respectivamente. O pó de cinco sementes de plantas exibiu efeitos bacteriostáticos e bactericidas com MIC's 20 e MBC 40 mg / ml contra K. pneumonia, enquanto MIC's 40 e MBC 60 mg / ml contra S. aureus. Os resultados deste estudo indicaram que os pós de sementes de plantas apresentam promissoras atividades antimicrobianas e suas potenciais aplicações em processos alimentícios. Ele poderia ser utilizado como alternativa medicinal natural em vez de substância química.
Asunto(s)
Cucurbita pepo , Enfermedades Transmitidas por los Alimentos/parasitología , Enfermedades Transmitidas por los Alimentos/tratamiento farmacológico , Enfermedades Transmitidas por los Alimentos/virología , Sesamum , Técnicas In VitroRESUMEN
Abstract In this research, some plant seeds powder was evaluated to find their potential effect to rule diseases of food poisoning. Antimicrobial effect of five plant seeds was examined contra Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella. pneumonia and Candida albicans by using well diffusion method. Antimicrobial activity studies revealed high potential activity of plant seeds powder of Nigella sativa L., cucurbita pepo, Sesamum radiatum, Trigonella foenum-graecum, Linum usitatissimum with variable efficiency contra tested microbial strains with concentration of 100 mg/ml, except Sesamum radiatum scored no effect. The T. foenum and N. sativa seed powder showed the largest inhibition zone (24-20 mm) contra K. pneumonia, followed by S. aureus (20-18 mm) and C. albicans (15mm) respectively. The five plant seeds powder exhibited bacteriostatic and bactericidal effects with MICs 20 and MBC 40 mg/ml against K. pneumonia, and MICs 40 and MBC 60 mg/ml against S. aureus. The results of this study indicated that plants seeds powder have promising antimicrobial activities and their potential applications in food process. It could be utilized as a natural medicinal alternative instead of chemical substance.
Resumo Nesta pesquisa, o pó de sementes de plantas foi avaliado para encontrar seu efeito potencial no controle de doenças de intoxicação alimentar. O efeito antimicrobiano de cinco sementes de plantas foi examinado contra Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia e Candida albicans usando o método de difusão bem. Estudos de atividade antimicrobiana revelaram alto potencial de atividade de sementes de plantas em pó de Nigella sativa L., Cucurbita pepo, Sesamum radiatum, Trigonella foenum-graecum, Linum usitatissimum com eficiência variável contra cepas microbianas testadas com concentração de 100 mg / ml, exceto Sesamum radiatum com pontuação não efeito. O pó de sementes de T. foenum e N. sativa apresentou a maior zona de inibição (24-20 mm) contra K. pneumonia, seguido por S. aureus (20-18 mm) e C. albicans (15 mm), respectivamente. O pó de cinco sementes de plantas exibiu efeitos bacteriostáticos e bactericidas com MICs 20 e MBC 40 mg / ml contra K. pneumonia, enquanto MICs 40 e MBC 60 mg / ml contra S. aureus. Os resultados deste estudo indicaram que os pós de sementes de plantas apresentam promissoras atividades antimicrobianas e suas potenciais aplicações em processos alimentícios. Ele poderia ser utilizado como alternativa medicinal natural em vez de substância química.
RESUMEN
Members of the family Diclidophoridae are potentially dangerous species for the puffer fish aquaculture worldwide. They are parasitic polyopisthocotyleans, with a posterior haptor equipped with clamps for attachment to the host's surface, allowing the worm to resist the flow of water to maintain its position on gills. The anterior body of the worm is deformable, allows the worm to feed on blood sucked from fish gills. The present study is the first description of a Heterobothrium species from the gills of the tiger puffer Lagocephalus sceleratus (Tetraodontidae) from the coasts of the Arabian Gulf at Jubail, Saudi Arabia morphologically by light microscopy as well as by molecular analysis of the parasite partial 28S rRNA through multiple sequence alignments and phylogeny by maximum likelihood analysis which is provided for the first time for the described species. Seventeen tiger puffer fish were captured alive from marine water off Saudi Arabia; gills were separated and further examined for parasitic infection. Nine fish were found infected with a monogenean parasite which was robust, equipped by two buccal organs at the tapered anterior end; the posterior haptor was rectangular with four symmetrically arranged clamps, with no isthmus. Marginal hooks absent. Ovary elongated, U-shaped, testes numerous, irregularly shaped and extended from the posterior part of the ovary to the anterior margin of the haptor. Copulatory organ muscular, as a spherical cup armed with 12 to 15 genital hooks. The molecular analysis of the parasite 28s rRNA and phylogeny revealed a percentage of identities between 87.47-89.09%, with Diclidophoridae species within the monophyletic clade of Mazocraeidea where a maximum percentage of 89.09% were obtained for the morphologically different sister taxon H. okamotoi. The results obtained from molecular analysis are consistent with the conclusions drawn from morphological classification where that the parasite recorded was morphologically similar to H. lamothei which was not characterized by molecular analysis before. The recovered sequences were deposited into the GeneBank under accession number MT322610.(AU)
Os membros da família Diclidophoridae são espécies potencialmente perigosas para a aquicultura de peixes puffer em todo o mundo. Eles são parasitas poliopisthocotyleans, com uma hélice posterior equipada com pinças para fixação na superfície do hospedeiro, permitindo que o verme resista ao fluxo de água para manter sua posição nas brânquias. O corpo anterior do verme é deformável, e permite que o verme se alimente de sangue sugado das guelras dos peixes. O presente estudo é a primeira descrição de uma espécie Heterobothrium das guelras do tigre Lagocephalus sceleratus (Tetraodontidae) das costas do Golfo Arábico em Jubail, Arábia Saudita, usando morfologia por microscopia leve, bem como análise molecular do rRNA parcial do parasita 28S através de alinhamentos de sequências múltiplas e filogenia por análise de máxima verossimilhança que é fornecida pela primeira vez para as espécies descritas. Dezessete peixes tigre puffer foram capturados vivos da água marinha da Arábia Saudita; as brânquias foram separadas e mais tarde examinadas para detecção de infecção parasitária. Nove peixes foram encontrados infectados por um parasita monogênio robusto, equipado por dois órgãos bucais na extremidade anterior afilada; o hortetor posterior era retangular com quatro pinças dispostas simetricamente, sem istmo. Ausência de ganchos marginais. Ovário alongado, em forma de U, testículos numerosos, de forma irregular e estendido desde a parte posterior do ovário até a margem anterior do hortelino. Órgão copulatório muscular, como um copo esférico armado com 12 a 15 ganchos genitais. A análise molecular do parasita 28s rRNA e filogenia revelou uma porcentagem de identidades entre 87,47-89,09%, com espécies Diclidophoridae dentro do clade monofilético de Mazocraeidea onde uma porcentagem máxima de 89,09% foi obtida para o táxon-irmão morfologicamente diferente H. okamotoi. Os resultados obtidos da análise molecular são consistentes com as conclusões tiradas da classificação morfológica onde o parasita registrado era morfologicamente semelhante ao H. lamothei que não era caracterizado pela análise molecular antes. As sequências recuperadas foram depositadas no GeneBank sob o número de acesso MT322610.(AU)
Asunto(s)
Animales , Platelmintos/anatomía & histología , Infecciones por Trematodos/veterinaria , Tetraodontiformes/parasitología , Filogenia , Arabia SauditaRESUMEN
OBJECTIVES: The aim of this systematic review was to critically analyze previously published studies of the effects of dentin surface pretreatment with deproteinizing agents on the bonding of self-etch (SE) adhesives to dentin. Additionally, a meta-analysis was conducted to quantify the effects of the above-mentioned surface pretreatment methods on the bonding of SE adhesives to dentin. MATERIALS AND METHODS: An electronic search was performed using the following databases: Scopus, PubMed and ScienceDirect. The online search was performed using the following keywords: ‘dentin’ or ‘hypochlorous acid’ or ‘sodium hypochlorite’ and ‘self-etch adhesive.’ The following categories were excluded during the assessment process: non-English articles, randomized clinical trials, case reports, animal studies, and review articles. The reviewed studies were subjected to meta-analysis to quantify the effect of the application time and concentration of sodium hypochlorite (NaOCl) and hypochlorous acid (HOCl) deproteinizing agents on bonding to dentin. RESULTS: Only 9 laboratory studies fit the inclusion criteria of this systematic review. The results of the meta-analysis revealed that the pooled average microtensile bond strength values to dentin pre-treated with deproteinizing agents (15.71 MPa) was significantly lower than those of the non-treated control group (20.94 MPa). CONCLUSIONS: In light of the currently available scientific evidence, dentin surface pretreatment with deproteinizing agents does not enhance the bonding of SE adhesives to dentin. The HOCl deproteinizing agent exhibited minimal adverse effects on bonding to dentin in comparison with NaOCl solutions.
Asunto(s)
Animales , Adhesivos , Dentina , Ácido Hipocloroso , Capa de Barro Dentinario , Hipoclorito de SodioRESUMEN
OBJECTIVES: The aims of this study were to conduct a systematic review of the microtensile bond strength (µTBS) of multi-mode adhesives to dentin and to perform a meta-analysis to assess the significance of differences in the µTBS of one of the most commonly used universal adhesives (Scotchbond Universal, 3M ESPE) depending on whether the etch-and-rinse or self-etch mode was used. MATERIALS AND METHODS: An electronic search was performed of MEDLINE/PubMed, ScienceDirect, and EBSCOhost. Laboratory studies that evaluated the µTBS of multi-mode adhesives to dentin using either the etch-and-rinse or self-etch mode were selected. A meta-analysis was conducted of the reviewed studies to quantify the differences in the µTBS of Scotchbond Universal adhesive. RESULTS: Only 10 studies fulfilled the inclusion criteria for the systematic review. Extensive variation was found in the restorative materials, testing methodologies, and failure mode in the reviewed articles. Furthermore, variation was also observed in the dimensions of the microtensile testing beams. The meta-analysis showed no statistically significant difference between the etch-and-rinse and self-etch modes for Scotchbond Universal adhesive (p > 0.05). CONCLUSIONS: Multi-mode ‘universal’ adhesives can achieve substantial bonding to dentin, regardless of the used modes (either etch-and-rinse or self-etch).
Asunto(s)
Adhesivos , Dentina , Recubrimientos DentinariosRESUMEN
Due to its extreme density, depleted Uranium [DU] has recently entered the warfare industry and became a major pollutant to the biosphere. Although DU is less radioactive than natural Uranium, it still retains all its chemical toxicity. Limited data exists regarding the longterm hazards of DU on humans, however, it is suspected to be a major toxic and mutagenic agent. Literature review reveals the scarcity of the World Health Organization's knowledge regarding related DU-malignancies. Battlefield reports documented a steady rise of malignancies and newborn malformations after war, that is, leukemia in the Balkans, and congenital anomalies and Kaposi sarcoma [KS] in Iraq. Kaposi sarcoma in Iraq has a quite aggressive behavior compared with the classic KS before, suggesting a potential relation with DU, and possibly a different DU related KS-type. Children are more susceptible to radiation than adults. This enlarges the responsibility of the medical communities for an evidence-based attitude towards DU, and to ban its use until proven otherwise. We, as medical bodies have a human approach - stand with man not to be mistreated, and with green norms, which veto all suspected pollutants of the planet. Until further notice, DU should be thoroughly checked for safety, before it kills.
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To investigate the relationship between cluster of differentiation [CD]36 gene variant rs1761667 [G>A] and metabolic syndrome [MetS] and its components in Egyptian patients. This case-control study was conducted on MetS patients attending Suez Canal University Hospital, Egypt from November 2010 to October 2011. Peripheral blood was collected from 100 patients and 100 healthy controls for DNA extraction. The single nucleotide polymorphism [SNP] CD36 gene rs1761667 G>A was genotyped using realtime polymerase chain reaction, and the allele discrimination technique. Distribution of CD36 genotypes in the patient group was AA [n=25], AG [n=70], and GG [n=5], while in the control group it was AA [n=51], AG [n=48], and GG [n=1]. Both AG and GG genotypes were significantly more prevalent among MetS patients [p<0.001]. The odds ratio [OR] for the high risk allele [G] is 2 with 95% confidence interval from 1.30-3.07 [p<0.001]. Patients with genotypes AG and GG had significantly higher systolic blood pressure, wider waist circumstance, and higher degree of dyslipidemia [p<0.001] than patients with genotype AA. Our findings show that CD36 rs1761667 SNP is positively associated with increased risk of MetS and its components with genotype AG heterozygotes showing highest frequency among MetS patients.
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To evaluate the effectiveness of small group teaching [SGT] in improving the undergraduate medical students' knowledge and skills. This study took place at the College of Medicine, Taibah University, Madina, Kingdom of Saudi Arabia between September 2011 and September 2012. Small group teaching was applied by the surgery department. In this prospective study, fifth year students were divided into groups of 8 students, and teaching strategies of SGT were applied. The marks in the clinical examinations of long case and objective structured clinical examination [OSCE] of the students with a traditional teaching cohort of 2010-2011 were compared to a SGT cohort of 2011- 2012. Data were analyzed by comparing the means, standard error, and standard deviation. One hundred and sixty-four students were incorporated, 82 students for each year [41 males and 41 females] in each group. The analysis showed a statistical significant difference in marks obtained by male and female students of both cohorts [p=0.000]. In the 2011-2012 group, male students' mean score was 43.1 +/- 2.99 which was higher than the 2010-2011 male students' [mean +/- SD: 38.7 +/- 2.81; p=0.000]. Similarly, the 2011-2012 female students attained a higher mean score than those in the 2010-2011 [39.8 +/- 4.0 and 35.6 +/- 3.88] [p=0.000]. Small group teaching is a valuable strategy in enhancing students' performance in the clinical settings. Small group teaching can be applied to other clinical disciplines of the medical curriculum for production of safe and clinically competent graduates
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To present the incidence and spectrum of anorectal malformations [ARMs] and associated anomalies, and to compare the findings with published literature. This is a retrospective study conducted during the period January 2011 to December 2011. We reviewed the medical charts of all cases with ARMs admitted to Al-Madinah Maternity and Children Hospital, Madinah, Kingdom of Saudi Arabia during 1998-2010. The incidence and spectrum of ARMs, associated regional anomalies, and those with a positive family history of ARMs were identified. The 95% confidence interval and Chi square trend test were used to quantify the significance of variation in annual incidence. One hundred and eighty-eight cases of ARMs were detected from 189,145 live births with an incidence of approximately 1/1000 live births with a male-to-female ratio of 1.9:1. The incidence showed yearly stability [p=0.3509]. The most common ARMs was perineal fistula [32.9%]. There was a statistically significant gender difference [p=0.000]. The most common in boys was rectourethral fistula [47.2%] and in girls was vestibular fistula [46.2%]. Isolated non-familial ARMs was found in 106 [56.3%], isolated familial 9 [4.7%], and associated ARMs in 73 [38.8%] cases. In terms of associated anomalies, genitourinary [34%], and cardiovascular [19.2%] systems reported a high incidence. The incidence of ARMs in Madinah Kingdom of Saudi Arabia, is higher than the reported data. Isolated ARMs was more common than the associated category, and the familial one was rarely reported
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To examine the anatomy of the azygos vein AV using different parameters. Therefore, the diameter of the AV at its opening into the superior vena cava, the opening level of the AV into the superior vena cava, and the position of the AV, with respect to the vertebral column and carina, were examined by CT. Chest CTs of 103 cases [42 female and 61 male] were reviewed at the Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey between July 2004 and February 2005. The CT examinations were performed with a Philips AU E1 spiral CT [Rotterdam, Netherlands] with the following parameters: 120 Hv; 200 mAs; slice thickness: 7 mm; pitch: 1; reconstruction index: 7 mm. The results were statistically analyzed. The diameter of the AV at the opening into the superior vena cava ranged between 4.3 mm and 16 mm. The AV was in the midline in 41 cases. The arching and opening level of the AV was at the fifth thoracic vertebra in most cases. The opening level was most often at the same level as the carina. Hemiazygos veins were detected in 90 patients. The parameters measured in this study may be useful in surgical procedures of the mediastinum and during the interpretation of chest radiographs
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Humanos , Masculino , Femenino , Tomografía Computarizada por Rayos X , Vena Cava Inferior , Mediastino/cirugía , Vena Ácigos/anatomía & histologíaRESUMEN
Hyperbaric oxygen therapy [HBOT] is an important adjunct in the management of wound problems, which exist in chronic oxygen deficiency and in which the local oxygen tension is below optimal of healing. This study aims to evaluate the effect of HBOT intervention guidelines on knowledge and practices of patients with chronic wounds. A quasi experimental design was used. This study was conducted at the Hyperbaric Oxygen Therapy Unit, affiliated to Naser Institute Hospital. A purposive sample included 40 adult patients with chronic wounds [Diabetic foot ulcers, venous leg ulcers and pressure ulcers]. 1] Patients' interviewing questionnaire sheet to assess patients' knowledge [pre/post tests], 2] An observation checklist to evaluate patient's practices [pre/post tests], 3] Anxiety Rating Scale to determine patients' anxiety level [pre/post tests], 4] Developed guidelines, 5] Patient condition assessment: wound symptoms chart to assess symptoms experienced by the patients, and wound assessment parameter scoring tool to assess wound healing [pre/post treatment]. There is a lack of knowledge and practices among the study sample. Statistically significant differences were also found between pre/post guidelines regarding to their knowledge and practices in relation to HBOT. In addition, patients had a higher level of anxiety in the pre test, while it decreased in post tests. The HBOT intervention guidelines were helpful on the improvement of knowledge and practices of the patients with chronic wounds. There is a need for sustained patients' educational sessions, HBOT should be available for all patients with chronic wounds. Further studies should be done on a large number of subjects for evidence of results and generalization
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Humanos , Masculino , Femenino , Heridas y Lesiones , Enfermedad Crónica , Úlcera del Pie , Úlcera Varicosa , Úlcera por Presión , Encuestas y Cuestionarios , Conocimiento , Estudios de Seguimiento , Guías de Práctica Clínica como AsuntoRESUMEN
Our aim was to investigate the microscopic surface structural alteration in hair with hereditary trichodysplasia. This article presents the results of light and scanning electron microscopy [SEM] examination of cases having hereditary trichodysplasia. The biopsy specimens were obtained from 2 girls of ages 3 and 5-years, Department of Pediatrics, Faculty of Medicine, Hacettepe University in 2001. A large number of hair specimens were obtained from these 2 cases having hereditary trichodysplasia. Routine light microscopic and SEM procedure was performed on the tissue specimen, and then they were examined by light microscopy and SEM. Hair specimens taken from both patients had great similarities. Our results reveal that the atypical looking hair were flattened, twisted and partly scattered at the end. Moreover, these hairs had sheath structures with abnormal proliferation and these structures were damaged, the cuticles had fractures and were degenerative. There is only a small number of SEM studies in literature reporting the ultrastructural changes of hereditary trichodysplasia. Scanning electron microscopy is a 3 dimensional examination technique revealing easily comparable images and it is indispensable for diagnosis in various tissues which permit considerable magnification. As it is used in the hereditary trichodysplasia syndrome its routine usage in many dermatologic and hair diseases will result in valuable contributions to scientific literature
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Humanos , Femenino , Hipotricosis/genética , Hipotricosis/etiología , Cabello/patología , Microscopía Electrónica de Rastreo , Enfermedades Genéticas CongénitasRESUMEN
To ascertain the type of skin diseases in Najran General Hospital as a rough pattern of skin diseases in Najran region and to compare this with other similar regional studies in the Kingdom of Saudi Arabia [KSA]. A retrospective 12 months study of the common skin dermatoses, which were recorded in Najran General Hospital, Najran, KSA, within the period December 2000 to December 2001. We recorded 1192 new patients within the study period, 37% had one of the dermatitis or eczema group of diseases, 12.75% had acne, 7% had vitiligo, 5.9% had viral infections 5.6% had superficial mycoses, 5% had bacterial infections, 1.51% had psoriasis and only 1.1% had lichen planus. By comparison, the incidence of dermatitis or eczema, acne and vitiligo was slightly higher in Najran compared to other regions such as Asir, Hail, Al-Jouf and Jeddah, KSA owing, probably, to the genetic predilection of Najran community to these disorders. Najran was lower than others in psoriasis and in lichen planus, but in minimal deviations. However, Najran was comparable to others in infective diseases including viral warts, superficial mycoses and bacterial infections. This comparison indicates that there were no large differences between Najran and other compared regions of KSA and this region is present in the heart of health development
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Humanos , Masculino , Femenino , Hospitales Generales , Estudios RetrospectivosRESUMEN
Five cases of toxicity due to consumption of an uncommon wild fruit called Colocynth are described. These cases were seen over a period of 2 years. Severe bouts of bloody diarrhea were encountered in these patients. The plant, its ingredients, the medicinal and other uses, features of toxicity and the management is discussed. Doctors are advised to be aware of this uncommon clinical problem
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Humanos , Masculino , Frutas , Rosales , Medicina TradicionalAsunto(s)
Humanos , Masculino , Celulitis (Flemón)/etiología , Lepra Dimorfa/diagnóstico , Biopsia , Enfermedades de la PielRESUMEN
We studied 60 elderly Patients undergoing lower limb orthopedic procedures classified as ASA III or IV. Lumbar continuous spinal anaesthesia [CSA] was performed using a 20 G epidural catheter through an 18 G Tuohy needle. Small local anaesthetic boluses of isobaric bupivacaine [0.5%] was injected to achieve the desired sensory level of anaesthesia. Demographic data, anaesthetic duration, local anaesthetic doses, sensory level to pinprick, Arterial blood pressure, heart rate, use of systemic sympathomimetics and complications were recorded. Sensory level was between TB-T12, maximal decrease in systolic, diastolic BP and heart rate was 30 +/- 12.5%, 16.8 +/- 9.5% and 15.6 +/- 5.8% respectively. IV ephedrine used in 25% of our patients. While postdural puncture headache [PDPH] occurred in 1,66% of cases. No postanaesthetic neurological deficit was recorded. We conclude that CSA using a standard epidural set and isobaric bupivacaine is feasible for L.L. surgery in high-risk elderly patients